![]() Please keep requesting imagines! If you like it, please follow more. ‘ Who knew that Dallas Winston was innocent at one time…’ you thought astonishingly within the safe vacancy of your own mind. That kid looked like Johnny…” and Dallas trailed off, leaving you gob smacked. Alabama-, Baldwin, Colbert, Cullman, Dallas, Escambia, Houston, Macon, Madison, Marshall, Montgomery, Morgan, Pickens, Randolph, Sumter, Winston. The way that kid’s brains shot out and he crumpled to the ground like a piece of meaningless paper did something to me. It didn’t even sound like Dally. “The sound was loud, almost left me deaf. That was one lesson I learnt in New York: If a guy pulls out a gun, he’s gonna use it.” his voice sounded different. I dare you.’ The kid said, and I didn’t think the guy would do it. Stupid thing to do, but the kid was rip roaring drunk, - as Two-bit would put it.” Dallas shakes his head, chucking his cigarette butt into the fire. “Next thing I know, the guy next to me pulls a gun out, presses the barrel right to the kids forehead.” Dallas stops for a moment, something tugs on the corner of his lips, but his eyes sting with guilt. It got you hurt and you were smart enough not to get yourself hurt.ĭallas’s languid slouch deepened, that look in his eyes extending into menacing animosity. “A kid from a rival gang came into our turf, boasting and what not about his gang. “No,” you shake your head, averting from saying much else, simply because pushing Dallas Winston was never a grand idea. “Did I ever tell you about that time I saw that kid get shot right before my eyes in New York?” Dallas’s voice remains aloof, his eyes wide and grim, but they were deep, like there was a story brewing up behind them. You were afraid that you had become mundane to him, but quite frankly, Dallas was thinking, reliving old memories of New York. The silence looms within the air, causing your stomach to twist and churn, nauseousness taking a hold of you. ![]() You give a gentle nod before Dallas pulls you even closer. There was a mini fire burning, crackling away as Dallas wrapped a secure arm around you. “You cold?” his voice seemed distant, aloof, as though he wasn’t really present with you, but in some far secluded land that only he had complete access to. 270 pages Completed DecemRiga The OutsidersSodapop CurtisDallas WinstonPonyboy CurtisSteve RandleJohnny CadeFanfictionRomanceLovePreferencesImaginesTwo Bit MatthewsDarry Curtis The title says it all AND Johnny and Dally are included This is for all those who LOVE the Outsiders. There was a silence that stretched for several minutes as you huddled up nice and close to Dallas in the vacant lot. Imagine: Dallas Winston opening up to you. I hope that you enjoy it, and sorry for the fact that it took ages for me to post it. Anonymous said: Can you do some Dallas Winston fluff about him really opening up to you in private? Lol just shower thoughts but I can’t write to save my life □□□Ī/N: Yeah of course, my lovely! I’ll be happy to write this for you. ![]()
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![]() Studies on thyroid cross-reactivity have focused primarily on pathogens and dietary proteins. We also determined that elevated levels of bisphenol-A bound to HSA significantly increases the risk for Parkinson’s disease and correlates with alpha-synuclein antibodies. Further research identified that these chemicals conjugated to HSA are associated with antibodies to neurological tissue involved in multiple sclerosis. In a study we published of 400 subjects, between 8–22% of individuals exhibited elevated levels of commonly exposed chemicals bound to human serum albumin. Ĭonjugation of chemicals bound to human serum albumin (HSA) is found with blood samples of healthy human blood donors. This leads to neoantigen formation, resulting in systemic T-cell or antibody immune responses against the haptens and self-proteins. Chemical molecules can bind directly or indirectly to circulating proteins after hepatic or extrahepatic conversion from prohapten to haptens, generating hapten–protein adducts. The alteration of protein topography leads to the binding of the antibody to the protein in the target sites. In addition, the binding of chemicals to self-proteins such as albumin, globulin, or hemoglobin leads to protein misfolding and induces a conformational change in the macromolecule. ![]() Reactivity of antibodies with chemicals bound to proteins has the potential to play a cross-reactive role in autoimmune thyroid disease and thyroid metabolism disruption. Cross-reactive interactions with various target sites of the thyroid axis may also lead to thyroid metabolism disruption. Furthermore, many antibody binding sites are polyfunctional and can accommodate more than one antigenic epitope and play a role in autoimmune disease. Cross-reactive antibodies from various infections have been found to play a role in autoimmune thyroid disease and thyroid metabolism dysfunction by binding to multiple target sites of the thyroid axis via cross-reactivity. These molecular interactions with the antigen–antibody binding sites can occur from a diverse list of antigen-promoted antibodies. Cross-reactivity of various antigens with self-tissue proteins can induce tissue-specific autoimmune diseases in susceptible subjects. The interactions of multiple antigenic antibodies with the same binding site are known as cross-reactivity. Immunological cross-reactivity is expressed when antibodies with similar amino acid homology or similar antibody surface topology bind to the same binding site. This laboratory analysis of immune reactivity between thyroid target sites and chemicals bound to HSA antibodies identifies a new mechanism by which chemicals can disrupt thyroid function. A significant decline in these reactions was observed. For demonstration of specificity of thyroid antibody binding to various haptenic chemicals bound to HSA, both serial dilution and inhibition studies were performed and proportioned to the dilution. ![]() ![]() Our study identified a new mechanism through which chemicals bound to circulating serum proteins lead to structural protein misfolding that creates neoantigens, resulting in the development of antibodies that bind to key target proteins of the thyroid axis through protein misfolding. We found that specific monoclonal or polyclonal antibodies developed against thyroid-stimulating hormone (TSH) receptor, 5′-deiodinase, thyroid peroxidase, thyroglobulin, thyroxine-binding globulin (TBG), thyroxine (T4), and triiodothyronine (T3) bound to various chemical HSA compounds. We investigated how antibodies made against thyroid target sites may bind to various chemical–albumin compounds where binding of the chemical has induced human serum albumin (HSA) misfolding. Alteration of peptides that share topological equivalence with alternating side chains can lead to the formation of binding surfaces that may mimic the antigenic structure of a variant peptide or protein. Cross-reactivity then can occur if epitopes of the protein share surface topology to similar binding sites. In some instances, when chemicals bind to proteins, they have the potential to induce a conformational change in the macromolecule that may misfold in such a way that makes it similar to the various target sites or act as a neoantigen without conformational change. ![]() ![]() ![]() Half-elf and Half-Orc are not listed, but are accounted for by Mixed Heritage, where you take the traits of one Heritage and the Gifts of another.Ĭultures include familiar things like Deep Dwarf and Hill Dwarf, Forest Gnome, High Elf and Wood Elf, but also new options such as Caravanner, Circusfolk,, Itinerant and Tyrannised. I might actually adopt this for humans in my next campaign. One thing that strikes me is this puts humans more on a level with the other Heritages ( unlike 5E in my opinion). Paragon gifts are one of Determined (when bloodied, you can turn an attack roll or saving throw into a natural 20 once per rest), Wind at your Back (Speed increases 10’, ignore difficult terrain when dashing, don’t provoke opportunity attacks from a creature you have attacked that turn) and Voracious Learner (expertise die in three different skill or tool proficiencies). Their Paragon Gifts at level 10 are gaining resistance to their breath weapon (or immunity if they already have resistance through Draconic Armour), and the Gifts improve to Impenetrable Draconic Armour (AC+1, claws become real melee weapons), Might Draconic Wings (40’ flying speed, can fly with medium or heavy armour, less likely to become fatigued) or Sleek Draconic Fins (faster and better underwater).įor another example, Human traits are Fast Learner (additional skill proficiency half time for training in armour, tool or weapon) and Intrepid (gain an expertise die per rest to use on an ability check, attack roll or saving throw) and Human Gifts are Diehard Survivor, Ingenious Focus or Spirited Traveller. Each Heritage has traits and gifts (where you choose a single heritage gift), and each Heritage also gains a Paragon gift at level 10.įor example, Dragonborn have dragon breath as their trait, and a choice of Draconic Armour (resistance and improved AC), Draconic Fins (swimming) or Draconic Wings (flying) as the Heritage Gift. ![]() Heritages are in strict alphabetical order and are Dragonborn, Dwarf, Elf, Gnome, Halfling, Human, Orc and Planetouched, which covers both Aasimar and Tiefling. Character generationĬharacters are comprised of Heritage and Culture (between them the equivalent of race), Background, Destiny, and Class. It covers character creation and abilities, equipment, ability scores, a small (10-page) section on adventuring, twice as much on combat and turn-based action, a large section on combat manoeuvres, and then over 100 pages of spells. ![]() So what’s in these weighty tomes? The Adventurer’s Guide See this side-by-side comparison to get the difference (modelled by our cat Sparky…) – left is Level Up, right is DMG: Having said that, the type is larger, so maybe the actual content is more similar than the page count would suggest. That contrasts with 316 pages for the PHB, 320 pages for the DMG, and 352 pages for the Monster Manual. The Adventurer’s Guide is 656 pages, Trials and Treasures is 370 pages, and Monstrous Menagerie is 531 pages. The first thing which struck me was just how large these tomes are. Monstrous Menagerie – the equivalent of the Monster Manual.Trials and Treasures – the equivalent of the Dungeon Master’s Guide.Adventurer’s Guide – the equivalent of the Player’s Handbook.Like 5E, the core rulebooks are organised into three volumes: I have read part way through the PDFs, but I find that having the physical copies makes me more inspired to just pick them up and browse. The PDFs dropped in November, and the print versions are now out. Level Up A5E is a rethinking of D&D Fifth Edition with the benefit of 5 years of practice and hindsight. ![]() ![]() Water leaks – This is pretty obvious and certainly one of the leading causes in Toronto to repair washers. But if your washing machine needs more or less water, that’s also a sign that something is off. Too many drums in the water? You have more problems than I think we could fix. Too little water in the drum? Also not OK. Water level issues – Too much water in the drum? Not OK. Think of your walking washer less as a thrill ride for your children and more an early detection of a bigger problem down the track. But the sloshing water and excessive movement on the drum and belts can lead to issues down the road. Your washer could still work as advertised, still cleaning your clothes well. Walking washers – It’s not that the “walking” is the issue. Regardless of what caused your washing machine to break down, you should know that there is a science to properly repairing a washing machine. Plus, if you book a virtual consult with us, not only will we diagnose the appliance issue over the phone, but we’ll also walk you through the steps to troubleshoot the repair yourself. We repair all kinds of washers including:īook a free service quote below with one of our leading-class appliance repair technicians, we’d be happy to assist you in any way with your washer repair project. No matter the appliance brand, make, or model, the Man with a Wrench team has you covered. Our team of dedicated technicians has spent years in the appliance repair industry boosting up their skills, and thus far we haven’t run into an appliance we couldn’t fix. We was polite.YOUR LOCAL WASHING MACHINE REPAIR SERVICEĪt Man with a Wrench, we are happy to service any of your washing machine repair, installation, and maintenance needs across all of Southern Ontario and Toronto. "Mike provided a great overall service which included ordering specialist parts for my dishwasher.
![]() “There were no possibilities to continue,” confirms Orrego, who moved to Isla Negra for a few months with Eduardo Gatti. The burning of their masters and the persecution of artists. could not survive the closing of spaces that followed the arrival of the military in La Moneda. After the recording of the second album, after reflecting on the festival experience, the band decided that they would not do any more lyrics, that they would abandon the acoustic instruments and that from then on they would be called Parafina. part of the group lived as a community in an old convent on the border of the communes of Ñuñoa and La Reina (La Manchufela, they called it). Upon returning from the catastrophic performance, the dressing room awaited them with an eloquent line: “Get out of here, shitty hippies.”. The pure acoustic sound of the group was lost among the furious screams of the monster of the Fifth. “As soon as the entertainer mentioned the name of the Blops, it was not necessary for the musicians to appear on stage for the public to boo them until they finished their presentation. They were part of the Dicap artists and were mercilessly booed by a audience that associated their name with the Unidad Popular. The band performed at the Viña del Mar Festival for three nights in 1971. When Blops (1970) appeared, they never imagined that this song would be precisely their great legacy to Chilean popular music. ![]() At the end of those sessions, and almost accidentally, they decided to include a composition by Eduardo Gatti that they barely knew: “Los momentoes”. he label gave them a few days of study, during which they recorded their first nine songs. Surprisingly, the Communist Party label, Dicap, was the only one that agreed to release an album by the Blops, despite the ideological mistrust aroused by their rather hippie orientation, their open sympathy towards marijuana, and their lack of greater commitment. they made the decision to start composing their own songs. its first repertoire with covers of bands like The Doors, The Who and the Rolling Stones. classic on the scale of “Los Momentos” and an impact that, although never massive, had a deep impact on a sector of the public and the Chilean music community. ![]() After its dissolution, in 1973, its three albums constituted a lost heritage until the personal effort of its members allowed its reissue, in 2001. was one of the few bands of the time that was able to transcend its Anglo-Saxon inspiration to give way to original creations with a powerful identity of their own. Jorge Leiva recounts Los Blops’ history and legacy: The song was from the “ebut from the experimental folk/rock band in the revolutionary days of the late 60’s in Chile” ( ) - so revolutionary that Los Blops were booed by right-wing audiences, considered “sh*tty hippies”, but at the same time viewed with distrust by the Communists because of “their rather hippie orientation, their open sympathy towards marijuana, and their lack of greater commitment”! () THE GREATEST SONGS OF THE 1960s THAT NO ONE HAS EVER HEARDĥ41) Los Blops - “Los Momentos”/ (“The Moments”)*Ī stunning folk rock song from Chile that “would become a classic of Chilean popular music” ( ) and for Los Blops - the band’s name “inspired by the sound of a drop of water hitting the ground their great legacy to Chilean popular music.” () ![]() ![]() ![]() Testing or stool examinations will distinguish infectious or parasitic organisms, bacterial toxins, blood, fat, electrolytes, white blood cells, and potential etiological organisms for diarrhea.Ĥ. Assessment of defecation pattern will help direct treatment. ![]() A person can have a bowel movement anywhere from one to three times a day at the most, or three times a week at the least, and still be considered regular, as long as it’s their usual pattern. What’s normal for one person may not be normal for another. Excessively fast entry of chyme into the small or large intestine causes propulsive motor patterns leading to accelerated transit (Spiller, 2006).Įveryone’s bowels are unique to them. It can be cramp-like, achy, dull, or sharp. Abdominal pain or “stomachache” can be felt between the chest and pelvis. Many patients with acute diarrhea, regardless of cause, experience gas, cramps, bloating, distention, flatulence, nausea, vomiting, and abdominal pain. Physicians have used increased frequency of defecation or increased stool weight as major criteria and distinguish acute diarrhea (Schiller et al., 2016). Normal stool frequency ranges from three times a week to three times a day. Patients differ in their definition of diarrhea, noting loose stool consistency, increased frequency, the urgency of bowel movements, or incontinence as key symptoms. These assessment findings are usually linked with diarrhea. Assess for abdominal discomfort, pain, cramping, frequency, urgency, loose or liquid stools, and hyperactive bowel sensations. Within 24 hours of nursing interventions, the patient re-establishes and maintains a normal pattern of bowel functioning.Ī thorough assessment is important to ascertain potential problems that may have led to diarrhea and handle any conflict that may appear during nursing care.ġ.Within 24 hours of nursing interventions, the patient will consume at least 1,500 to 2,000 mL of clear liquids to maintain good skin turgor and normal weight.Within 8 hours of nursing interventions, the patient verbalizes understanding of diarrhea’s causes and the rationale for treatment.The following are the common goals and expected outcomes for Diarrhea: Hyperactive bowel sounds (borborygmi) or sensations.Surgical procedures: bowel resection, gastrectomyĪ patient with diarrhea may report the following signs and symptoms:.Mucosal inflammation: Crohn’s disease or ulcerative colitis.Malabsorption (e.g., lactase deficiency).Enteric infections: viral, bacterial, or parasitic.The following are the common causes and factors related to the development of diarrhea: Additionally, nurses and the healthcare team members must take precautions to prevent transmission of infection associated with some causes of diarrhea. Problems associated with diarrhea include fluid and electrolyte imbalances, impaired nutrition, and altered skin integrity. ![]() However, severe diarrhea can lead to dehydration or severe nutritional problems. Mild diarrhea cases can recover in a few days. It may also be due to infection, inflammatory bowel diseases, side effects of drugs, increased osmotic loads, radiation, or increased intestinal motility.ĭiarrhea can be an acute or severe problem. It may arise from various factors, including malabsorption disorders, increased secretion of fluid by the intestinal mucosa, and hypermotility of the intestine. What is Diarrhea?ĭiarrhea is defined as an increase in the frequency of bowel movements and the water content and volume of the waste. Learn about the nursing assessment, nursing interventions, goals and nursing diagnosis for diarrhea in this guide. Use this nursing care plan and management guide to help care for patients with diagnosis of diarrhea. ![]() ![]() ![]() ![]() Prices listed here were accurate at the time of publication on. Buy products such as Pen + Gear Extra Large Polyester Binder Pouch Pencil Case, Black, 11 x 8.75 at Walmart and. BOOKS TO COLLECT COINS PENCIL BAGS PENCIL SHARPENERS COMMEMORATIVE OR. Shop for Pencil Pouches in Pencil Holders. It also removes the stress of worrying whether the gift will arrive in time! No matter how you shop, deals and discounts can be found while you find the perfect home office gifts. BULLETIN BOARDS ERASABLE MEMO BOARDS PEN AND PENCIL HOLDERS PAPER CLIP. Vnieetsr Large Pencil Case Big Capacity Pencil Bag Large Storage Pouch 3 Compartments Desk Organizer Marker Pen Case Simple Stationery Bag Pencil Holder. Planning ahead for a birthday gift can also save money if you land a terrific deal around a holiday. 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Does it need to be a more comfortable space? Purchase a home office gift that solves a problem they may not even realize they have.As you begin your hunt for the best home office gifts, take a look at these considerations to help you narrow down your search. Our bag organizers, wallets, jewelry and beauty. Gift buying doesn’t have to be a headache. Clean, timeless designs in Italian and Argentinian leather that bring beauty and purpose to your everyday. Photo: How to Choose the Best Home Office Gifts ![]() ![]() ![]() You can even obtain bundles of 100 Times Tables Chart. These printables are suitable for home schooling or length learning. You can also get worksheets determined by your child’s get older. You can implement them any courses plus they are also made to simply be tailored. You can get your worksheets in a PDF document, which is very easy to printing. 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The first time I was blamed saying I used scratched DVDs. The car was brought in for service to fix the issue. Needless to say, my kids never have been able to watch a movie from beginning to end without it losing connection. Almost immediately we noticed problems with the car – the navigation system didn’t work and the DVD system was broken – it constantly lost connection. We were so excited because it was our first car with navigation and the rear entertainment system! My kids were so happy to have this feature however our excitement was short lived. ![]() Here is what one customer said on Edmunds, “In October 2017 my family leased a 2018 odyssey. Sadly, most kids aren’t able to enjoy their favorite movies, mainly because of some electrical complaints. With a navigation system, rear DVD player and other amenities, it’s simple to keep the kids entertained on long drives. One of the reasons so many families purchase the Odyssey is because of all the high-tech gear included. ![]() ![]() For example, the variance of a latent variable is used for evaluating development across time and for gaining insight about differences between groups. Even though it is commonly ignored, the variance of a latent variable has been recognized as a useful source of information for some specific areas, in particular, longitudinal research and invariance analyses ( McArdle and Cattell, 1994 Schmitt and Kuljanin, 2008 McArdle, 2009). Such dependency does not endorse the variance of the latent variable as a reliable source of information.ĭespite the dependency on indicator selection, factor variance can be an important piece of information for evaluation. It is well-known that modifying scaling by replacing one indicator by another one changes the value of the variance among other consequences (e.g., Gonzalez and Griffin, 2001 Steiger, 2002). A reason for ignoring the variance as a source of information is its dependency on the indicator selected for scaling in order to achieve model identification. While also a parameter of the model, under factor analysis, the variance of the latent variable is largely ignored as a source of information for evaluation. In evaluating the results of factor analysis, the focus is usually on the factor loadings as related to the magnitude and the direction of the relationship to the latent variable. It enables the adaptation of scaling methods to the requirements of the field of application. The impact of the number of manifest variables on the scaled variance parameter can be modified and the range of possible values. ![]() Furthermore, it is shown that available scaling methods are in line with this constancy framework and that the criterion number included in some scaling methods enables modifications. It provides the basis for a scaling method that enables the comparison of the contribution of different latent variables of the same confirmatory factor model to observed scores, as for example, the contributions of trait and method latent variables. A constancy framework, based upon the underlying factor analysis formula that enables scaling by modifying components through scalar multiplication, is described a proof is included to demonstrate the constancy property of the framework. This paper investigates how the major outcome of a confirmatory factor investigation is preserved when scaling the variance of a latent variable by the various scaling methods. 3Department of Educational Studies, University of South Carolina, Columbia, SC, United States. ![]() 2Department of Psychology, University of Bern, Bern, Switzerland.1Institute of Psychology, Goethe University Frankfurt, Frankfurt, Germany. ![]() |